Preview

Бюллетень сибирской медицины

Расширенный поиск

Молекулярные и эпидемиологические основы аллергии к белкам коровьего молока

https://doi.org/10.20538/1682-0363-2011-6-86-92

Полный текст:

Аннотация

Аллергия к белкам коровьего молока характеризуется ранним дебютом и высокой распространенностью в детской популяции. В обзоре представлены современные данные о молекулярной структуре, физико-химических и аллергенных свойствах белковых компонентов коровьего молока. Изложены закономерности естественного течения пищевой аллергии и аспекты формирования толерантности к белкам данного продукта.

Об авторах

М. М. Федотова
Сибирский государственный медицинский университет
Россия

Федотова Марина Михайловна, аспирант кафедры факультетской педиатрии с курсом детских болезней лечебного факультета

тел. 8-906-956-8174



Л. М. Огородова
Сибирский государственный медицинский университет
Россия
заслуженный деятель науки РФ, д-р мед. наук, профессор, член-корреспондент РАМН, зав. кафедрой факультетской педиатрии с курсом детских болезней лечебного факультета


О. С. Фѐдорова
Сибирский государственный медицинский университет
Россия
канд. мед. наук, доцент кафедры факультетской педиатрии с курсом детских болезней лечебного факультета


Т. А. Евдокимова
Сибирский государственный медицинский университет
Россия
канд. мед. наук, докторант кафедры факультетской педиатрии с курсом детских болезней лечебного факультета


Список литературы

1. Балаболкин И.И., Соснина О.Б. Пищевая аллергия у детей и подростков//Рос. аллергол. журн. 2006. № 3. С. 44-52.

2. Лусс Л.В., Репина Т.Ю. Пищевая аллергия и пищевая непереносимость: принципы диагностики и терапии//Лечащий врач. 2004. № 7. С. 16-20.

3. Фёдорова О.С. Распространенность пищевой аллергии у детей в мировом очаге описторхоза//Бюл. сиб. медицины. 2010. Т. 9, № 5. С. 102-107.

4. Фёдорова О.С., Огородова Л.М., Солодовникова О.С. и др. Пищевая аллергия у детей: аспекты эпидемиологии и естественного течения//Педиатрия. 2009. Т. 87, № 2. С. 116-125.

5. Ah-Leung S., Bernard H., Bidat E. et al. Allergy to goat and sheep milk without allergy to cow's milk//Allergy. 2006. V. 61, № 11. P. 1358-1365.

6. Akdis M., Verhagen J., Taylor A. et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells//J. Exp. Med. 2004. V. 199. P. 1567-1575.

7. Anderson P.J., Brooks C.L., Berliner L.J. Functional identification of calcium binding residues in bovine alpha-lactalbumin//Biochemistry. 1997. V. 36, № 39. P. 11648-11654.

8. Aymard P., Durand D., Nicolai T. The effect of temperature and ionic strength on the dimerisation of beta-lactoglobulin//Int. J. Biol. Macromol. 1996. V. 19. P. 213-221.

9. Ball G., Shelton M.J., Walsh B.J. et al. A major continuous epitope of bovine b-lactoglobulin recognized by human IgE binding//Clin. Exp. Allergy. 1994. V. 24. P. 758-764.

10. Baroglio C., Giuffrida M.G., Cantisani A. et al. Evidence for a common epitope between bovine alpha-lactalbumin and beta-lactoglobulin//Biol. Chem. 1998. V. 379, № 12. P. 1453-1456.

11. Bernard H., Creminon C., Yvon M. et al. Specificity of the human IgE response to the different purified caseins in allergy to cow's milk proteins//Int. Arch. Allergy Immunol. 1998. V. 115, № 3. P. 235-244.

12. Chapman M.D., Pomes A., Breitender H. Nomenclature and structural biology of allergens//J. Allergy Clin. Immunol. 2007. V. 119. № 2. P. 414-420.

13. Chatchatee P., Jarvinen K.M., Bardina L. et al. Identification of IgE-and IgG-binding epitopes on alpha(s1)-casein: differences in patients with persistent and transient cow's milk allergy//J. Allergy Clin. Immunol. 2001. V. 107, № 2. P. 379-383.

14. Ehn B.M., Ekstrand B., Bengtsson U. et al. Modification of IgE-binding during heat processing of the cow's milk allergen beta-lactoglobulin//J. Agric. Food Chem. 2004. V. 52, № 5. P. 1398-1403.

15. Fiocchi A., Brozek J., Ёnemann H.S. et al. World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines//WAO Journal. 2010. №4. P. 57-161.

16. Fiocchi A., Restani P., Riva E. et al. Heat treatment modifies the allergenicity of beef and bovine serum albumin//Allergy. 1998. V. 53, № 8. P. 798-802.

17. Fiocchi A., Terracciano L., Bouygue G.R. et al. Incremental prognostic factors associated with cow's milk allergy outcomes in infant and child referrals: the Milan Cow's MilkAllergy Cohort study//Ann. Allergy Asthma Immunol. 2008. V. 101. P. 166-173.

18. Han G.D., Matsuno M., Ito S. et al. Meat allergy: investigation of potential allergenic proteins in beef//Biosci. Biotechnol. Biochem. 2000. V. 64, № 9. P. 1887-1895.

19. Hill D.J., Firer M.A. Ball G. Natural history of cows milk allergy in children: immunological outcome over 2 years//Clin. Exp. Allergy. 1993. V. 23. P. 124-131.

20. Illi S., Von Muttius E., Lau S. et al. The natural course of atopic dermatitis from birth to age 7 years and association with asthma//J. Allergol. Clin. Immunol. 2004. V. 113. P. 925-938.

21. Lara-Villoslada F., Olivares M., Xaus J. The balance between caseins and whey proteins in cow's milk determines its allergenicity//J. Dairy Sci. 2005. V. 88, № 5. P. 1654-1660.

22. Levy Y. Segal N. Garty B. et al. Lessons from the clinical course of IgE-mediated cow milk allergy in Israel//Pediatr. Allergy Immunol. 2007. V. 18. P. 589-593.

23. Maynard F., Jost R., Wal J.M. Human IgE binding capacity of tryptic peptides from bovine alpha-lactalbumin//Int. Arch. Allergy Immunol. 1997. V. 113 (4). P. 478-488.

24. Monaci L., Tregoat V., van Hengel A.J. et al. Milk allergens, their characteristics and their detection in food: A review//Eur. Food Research Tech. 2006 V. 223 (2). P. 149-179.

25. Permyakov E.A., Berliner L.J. Alpha-Lactalbumin: structure and function//FEBS Lett. 2000. V. 473 (3). P. 269-274.

26. Restani P., Gaiaschi A., Plebani A. et al. Cross-reactivity between milk proteins from different animal species//Clin. Exp. Allergy. 1999. V. 29 (7). P. 997-1004.

27. Roberts G., Patel N., Levi-Schaffer F. et al. Food allergy as a risk-factor of life-threatening asthma in childhood a case-controlled study//J. Allergol. Clin. Immunol.2003. V. 112. P. 168-174.

28. Roehr C.C., Edenharter G., Reimann S. et al. Food allergy and non-allergic food hypersensitivity in children and adolescents//Clin. Exp. Allergy. 2004. V. 34. P. 1534-1541.

29. Rozenfeld P., Docena G.H., Anon M.C. et al. Detection and identification of a soy protein component that cross-reacts with caseins from cow's milk//Clin. Exp. Immunol. 2002 V. 130 (1). P. 49-58.

30. Ruiter B., Tregoat V., M'rabet L. et al. Characterization of T cell epitopes in alphas1-casein in cow's milk allergic, atopic and non-atopic children//Clin. Exp. Allergy. 2006. V. 36 (3). P. 303-310.

31. Saarinen K.M., Juntunen-Backman K., Kuitunen P. et al. Supplementary feeding in maternity hospitals and the risk of cow's milk allergy: a prospective study of 6209 infants//J. Allergy. Clin. Immunol. 1999. V. 104. P. 457-461.

32. Samson H. A. Update on food allergy//J. Allergy Clin. Immunol. 2004. V. 5. Р. 805-819.

33. Schmidt D.G., Meijer R.J., Slangen C.J. et al. Raising the pH of the pepsin-catalysed hydrolysis of bovine whey proteins increases the antigenicity of the hydrolysates//Clin. Exp. Allergy. 1995. V. 25 (10). P. 1007-1017.

34. Schrander JJ, Van Den Bogart JP. Cow's milk protein intolerance in infants under 1 year of age: a prospective epidemiological study//Eur. J. Pediatr. 1993. V. 152. P. 640-644.

35. Sicherer S.H., Sampson H.A. Cow's milk protein-specific IgE concentrations in two age groups of milk-allergic children and in children achieving clinical tolerance//Clin. Exp. Allergy. 1999. V. 29 (4). P. 507-512.

36. Skripak J.M., Nash S.D., Rowley H. et all. A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergy//J. Allergy Clin. Immunol. 2008. V. 122, № 6. P. 1154-1160. <http://www.jacionline.org/article/S0091-6749(08)01725-9/fulltext> <http://www.jacionline.org/article/S0091-6749(08)01725-9/fulltext>

37. Skripak J.M., Matsui E.C., Mudd K. et al. The natural history of IgE-mediated cow's milk allergy//J. Allergy Clin. Immunol. 2007. V. 120. P. 1172-1177.

38. Spuergin P, Walter M, Schiltz E. et al. Allergenicity of alpha-caseins from cow, sheep, and goat//Allergy 1997. V. 52. P. 293-298

39. Spuergin P., Mueller H., Walter M. Allergenic epitopes of bovine a S1-casein recognized by human IgE and IgG//Allergy. 1996. V. 51 (5). P. 306-312.

40. Suutari T.J., Valkonen K.H., Karttunen T.J. et al. IgE cross reactivity between reindeer and bovine milk beta-lactoglobulins in cow's milk allergic patients//J. Investig. Allergol. Clin. Immunol. 2006. V. 16 (5). P. 296-302.

41. Swaisgood H.E. Review and update of casein chemistry//J. Dairy Sci. 1993. V. 76 (10). P. 3054-3061.

42. Vanto T., Helppila S., Juntunen-Backman K. et al. Prediction of the development of tolerance to milk in children with cow milk hypersensitivity//J. Pediatr. 2004. V. 144. P. 218-222.

43. Vicente-Serrano J., Caballero M.L., Rodriguez-Perez R. et al. Sensitization to serum albumins in children allergic to cow's milk and epithelia//Pediatr. Allergy Immunol. 2007. V. 18 (6). P. 503-507.

44. Vila L., Beyer K., Jarvinen K.M. et al. Role of conformational and linear epitopes in the achievement of tolerance in cow's milk allergy//Clin. Exp. Allergy. 2001. V. 31. P. 1599-1606.

45. Wal J.M. Cow's milk proteins/allergens//Aim Allergy Asthma lmmunol. 2002. V. 89 (1). P. 3-10.

46. Weid T., Bulliard., Schiffrin E.J. Induction by a lactic acid bacterium of a population of CD4+ T cells with low proliferative capacity that produce transforming growth factor beta and interleukin-10//Clin. Diagn. Lab. Immunol. 2001. № 8. P. 695-701.

47. Witteman A.M., van Leeuwen J., van der Zee J. et al. Food allergens in house dust//Int. Arch. Allergy Immunol. 1995. V. 107 (4). P. 566-568.

48. Wong G.W., Mahesh P.A. Ogorodova L.M. et al. The EuroPrevall-INCO surveys on the prevalence of food allergies in children from China, India and Russia: the study methodology//Allergy. 2010. V. 65, № 3. P. 385-390


Для цитирования:


Федотова М.М., Огородова Л.М., Фѐдорова О.С., Евдокимова Т.А. Молекулярные и эпидемиологические основы аллергии к белкам коровьего молока. Бюллетень сибирской медицины. 2011;10(6):86-92. https://doi.org/10.20538/1682-0363-2011-6-86-92

For citation:


Fedotova M.M., Ogorodova L.M., Fyodorova O.S., Evdokimova T.A. Molecular and epidemiological basis of cow's milk allergy. Bulletin of Siberian Medicine. 2011;10(6):86-92. (In Russ.) https://doi.org/10.20538/1682-0363-2011-6-86-92

Просмотров: 207


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)