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Стоматологические проявления первичных иммунодефицитов

https://doi.org/10.20538/1682-0363-2019-3-144-154

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Аннотация

Для понимания современного состояния проблемы стоматологических проявлений первичных иммунодефицитов проанализирована соответствующая зарубежная литература. В статье описаны стоматологические проявления многих первичных иммунодефицитов, которые могут быть как вторичным, так и основным симптомом. Представлены синдром тяжелого комбинированного иммунодефицита, гипер-IgE синдром, синдромы Вискотта – Олдрича, Ди Джорджи, дефицит STIM1 и дефицит ORAI1, дефицит NEMO и дефицит IκBα, общая вариабельная иммунная недостаточность, X-сцепленная агаммаглобулинемия, гипер-IgM синдром, селективный дефицит IgA, аутоиммунный лимфопролиферативный синдром, аутоиммунный полиýндокринный синдром 1-го типа, синдром Чедиака – Хигаши, дефицит CD70, синдромы тяжелой врожденной нейтропении, дефициты адгезии лейкоцитов, локализованный агрессивный пародонтит, синдром Папийона – Лефевра, хронический кожно-слизистый кандидоз, синдром Маршалла, гипер-IgD синдром, синдром Айкарди – Гутьереса 7-го типа, синдром херувизма, синдром CANDLE (хронический атипичный нейтрофильный дерматит с липодистрофией), PAPA (пиогенный артрит, гангренозная пиодермия и акне), хронический рецидивирующий мультифокальном остеомиелит, периодонтальный синдром Элерса – Данло, дефицит С1-ингибитора. Приведены данные о роли секреторных иммуноглобулинов, определяемых в слюнной жидкости.

Об авторах

М. А. Долгих
Институт иммунологии и физиологии Уральского отделения РАН (ИИФ УрО РАН)
Россия

аспирант, 

620049, г. Екатеринбург, ул. Первомайская, 106



М. А. Болков
Институт иммунологии и физиологии Уральского отделения РАН (ИИФ УрО РАН); Уральский федеральный университет имени первого Президента России Б.Н. Ельцина
Россия

канд. мед. наук, ст. науч. сотрудник, 620049, г. Екатеринбург, ул. Первомайская, 106;

620002, г. Екатеринбург, ул. Мира, 19



И. А. Тузанкина
Институт иммунологии и физиологии Уральского отделения РАН (ИИФ УрО РАН); Уральский федеральный университет имени первого Президента России Б.Н. Ельцина
Россия

д-р мед. наук, заслуженный деятель науки Российской Федерации, профессор, гл. науч. сотрудник, 620049, г. Екатеринбург, ул. Первомайская, 106;

620002, г. Екатеринбург, ул. Мира, 19



Н. Г. Саркисян
Институт иммунологии и физиологии Уральского отделения РАН (ИИФ УрО РАН); Уральский федеральный университет имени первого Президента России Б.Н. Ельцина
Россия

канд. мед. наук., науч. сотрудник, 620049, г. Екатеринбург, ул. Первомайская, 106;

620002, г. Екатеринбург, ул. Мира, 19



Н. А. Овсепян
Институт иммунологии и физиологии Уральского отделения РАН (ИИФ УрО РАН)
Россия

аспирант,

620049, г. Екатеринбург, ул. Первомайская, 106



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Для цитирования:


Долгих М.А., Болков М.А., Тузанкина И.А., Саркисян Н.Г., Овсепян Н.А. Стоматологические проявления первичных иммунодефицитов. Бюллетень сибирской медицины. 2019;18(3):144-154. https://doi.org/10.20538/1682-0363-2019-3-144-154

For citation:


Dolgikh M.A., Bolkov M.A., Tuzankina I.A., Sarkisyan N.G., Hovsepyan N.A. Oral manifestations of primary immunodeficiencies. Bulletin of Siberian Medicine. 2019;18(3):144-154. (In Russ.) https://doi.org/10.20538/1682-0363-2019-3-144-154

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ISSN 1819-3684 (Online)