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Аллергический ринит и феномен энтопии

https://doi.org/10.20538/1682-0363-2020-3-137-143

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Аннотация

Представлен обзор современных исследований, посвященных недавно открытому явлению – феномену энтопии (локальной атопии), с точки зрения его фенотипов и эндотипов. Клиническим вариантом эндотипа энтопии является локальный аллергический ринит, новая патология, – объект исследований в современной иммунологии, аллергологии и оториноларингологии. Точные механизмы срыва толерантности к аллергенам при энтопии  остаются неясными. Между тем феномен энтопии может стать ключом для расшифровки нерешенных вопросов срыва аллергической толерантности в разных  анатомических сайтах. Обзор посвящен патогенезу, диагностическому алгоритму и проблеме выбора терапевтических подходов при локальном аллергическом рините.

Об авторах

А. В. Климов
Сибирский государственный медицинский университет (СибГМУ)
Россия

канд. мед. наук, ассистент, кафедра оториноларингологии

Россия, 634050, г. Toмск, Московский тракт, 2



О. В. Kaлюжин
Первый Московский медицинский государственный университет им. И.М. Сеченова
Россия

д-р мед. наук, профессор, кафедра клинической иммунологии и аллергологии

Россия, 119991, г. Moсква, ул. Трубецкая, 8/2



В. В. Kлимов
Сибирский государственный медицинский университет (СибГМУ)
Россия

д-р мед. наук, профессор, зав. кафедрой иммунологии и аллергологии

Россия, 634050, г. Toмск, Московский тракт, 2



В. С. Свиридова
Сибирский государственный медицинский университет (СибГМУ)
Россия

канд. мед. наук, доцент, кафедра иммунологии и аллергологии

Россия, 634050, г. Toмск, Московский тракт, 2



Список литературы

1. Coca A.F., Cooke R.A. On the classification of the phenomenon of hypersensitiveness. J. Immunol. 1923; 8: 163–182.

2. Bellanti J.A., Settipane R.A. The atopic disorders and atopy. “strange diseases” now better defined! Allergy Asthma Proc. 2017; 38 (4): 241–242. DOI: 10.2500/aap.2017.38.4074.

3. Ishizaka K., Ishizaka T., Hornbrook M.M. Physico-chemical properties of human reaginic antibody. IV. Presence of a unique immunoglobulin as a carrier of reaginic activity. J. Immunol. 1966; 97 (1): 75–85.

4. Gell P.G.H., Coombs R.R.A. eds. Clinical aspects of immunology. London: Blackwell, 1963.

5. Gross M. Why did evolution give us allergies? Current Biology. 2015; 25 (2): 53–55. DOI: 10.1016/j.cub.2015.01.002.

6. Tyagi N., Farnell E.J., Fitzsimmons C.M. et al. Comparisons of allergenic and metazoan parasite proteins: Allergy the price of immunity. PLOS Computational Biology. 2015; 11: e1004546. DOI: 10.1371/journal.pcbi.1004546.

7. Tamari M., Tanaka S., Hirota T. Genome-wide association studies of allergic diseases. Allergol. Int. 2013; 62 (1): 21–28. DOI: 10.2332/allergolint.13-RAI-0539.

8. Lyons J.J., Milner J.D. Primary atopic disorders. J. Exp. Med. 2018; 215 (4); 1009–1022. DOI: 10.1084/jem.20172306.

9. Tezza G., Mazzei F., Boner A. Epigenetics of allergy. Early Hum. Dev. 2013; 89 (1): S20–S21. DOI: 10.1016/S0378-3782(13)70007-0.

10. Thomas W.R. Hierarchy and molecular properties of house dust mite allergens. Allergology International. 2015; 64: 304–311. DOI: 10.1016/j.alit.2015.05.004.

11. Calderon M.A., Linnberg A., Kleine-Tebble J. et al. Respiratory allergy caused by house dust mites: What do we really know? J. Allergy Clin. Immunol. 2015; 136 (1): 38–48. DOI: 10.1016/j.jaci.2014.10.012.

12. Klimov V.V. From basic to clinical immunology. Springer Nature Switzerland AG, 2019: 377. DOI: 10.1007/978-3-030-03323-1.

13. Pali-Scholl I., Jensen-Jarolim E. The concept of allergen-associated molecular patterns (AAMP). Current Opinion in Immunology. 2016; 42: 113–118. DOI: 10.1016/j.coi.2016.08.004.

14. Metcalfe D.D., Pawankar R., Ackerman S.J. et al. Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases. World Allergy Organization J. 2016: 9 (7): 1–15. DOI: 10.1186/s40413-016-0094-3.

15. Krystel-Whittemore M., Dileepan K.N., Wood J.G. Mast cell: a multi-functional master cell. Frontiers in Immunology. 2016; 6 (620): 1–12. DOI: 10.3389/fimmu.2015.00620.

16. Jacobsen E.A., Helmers R.A., Lee J.J., Lee N.A. The expanding role(s) of eosinophils in health and disease. Blood. 2012: 120 (19): 3882–3890. DOI: 10.1182/blood-2012-06-330845.

17. Bantz S.K., Zhu Z., Zheng T. The Atopic march: Progression from atopic dermatitis to allergic rhinitis and asthma. J. Clin. Cell Immunol. 2014; 5 (4): 1–16. DOI: 10.4172/2155-9899.1000202.

18. Powe D.G., Bonnin A.J., Jones N.S. “Entopy”: Local allergy paradigm. Clin. Exp. Allergy. 2010; 40 (7): 987–997. DOI: 10.1111/j.1365-2222.2010.03536.x.

19. Rondón C., Canto G., Blanca M. Local allergic rhinitis: A new entity, characterization and further studies. Curr. Opinion in Allergy and Clin. Immun. 2010; 10 (1): 1–7. DOI: 10.1097/ACI.0b013e328334f5fb.

20. Incorvaia C., Fuiano N., Martignago I. et al. Local allergic rhinitis: Evolution of concepts. Clin. Transl. Allergy. 2017; 7 (38): 1–4. DOI: 10.1186/s13601-017-0174-7.

21. Yamana Y., Fukuda K., Ko R., Uchio E. Local allergic conjunctivitis: A phenotype of allergic conjunctivitis. Int. Ophthalmol. 2019; 39: 2539–2544. DOI: 10.1007/s10792- 019-01101-z.

22. Campo P., Eguiluz-Gracia I., Plaza-Serón M.C. et al. Bronchial asthma triggered by house dust mites in patients with local allergic rhinitis. Allergy. 2019; 74 (8): 1502–1510. DOI: 10.1111/all.13775.

23. Rondón C., Campo P., Togias A. et al. Local allergic rhinitis: Concept, pathophysiology, and management. J. Allergy Clin. Immunol. 2012; 129: 1460–1467. DOI: 10.1111/all.12002.

24. Altintoprak N., Kar M., Muluk N.B. et al. Update on local allergic rhinitis. Inter. J. Ped. Otorhinolaryngology. 2016; 87: 105–109. DOI: 10.1016/j.ijporl.2016.06.008.

25. Jung C.-G., Lee J.-H., Ban G.-Y. et al. Prevalence and clinical characteristics of local allergic rhinitis to house dust mites. Yonsei Med. J. 2017; 58 (5): 1047–1050. DOI: 10.3349/ymj.2017.58.5.1047.

26. Gomez E., Campo P., Rondón C. et al. Role of the basophil activation test in the diagnosis of local allergic rhinitis. J. Allergy Clin. Immunol. 2013; 132 (4): 975–976. DOI: 10.1016/j.jaci.2013.07.016.

27. Kılıç E., Kutlu A., Hastalıkları G. et al. Does local allergy (entopy) exists in asthma? J. of Clinical and Analytical Medicine. 2016. Letters to Editors from 01.02.2016. DOI: 10.4328/JCAM.3272.

28. Wisniewski J., Agrawal R., Woodfolk J.A. Mechanisms of tolerance in duction in allergic disease: Integrating current and emerging concepts. Clin. Exp. Allergy. 2013; 43 (2): 164–176. DOI :10.1111/cea.12016.

29. Passali D., Cingi C., Staffa P. et al. The international study of the allergic rhinitis survey: Outcomes from 4 geographical regions. Asia Pac. Allergy. 2018: 8 (1): e7. DOI: 10.5415/apallergy.2018.8.e7.

30. Romano M.R., James S., Farrington E. et al. The impact of perennial allergic rhinitis with/without allergic asthma on sleep, work and activity level. Allergy Asthma Clin. Immunol. 2019; 15: 81. DOI: 10.1186/s13223-019-0391-9.

31. Okubo K., Kurono Y., Ichimura K. et al. Japanese guidelines for allergic rhinitis 2017. Allergology International. 2017; 66 (2): 205–219. DOI: 10.1016/j.alit.2016.11.001.

32. Watts A.M., Cripps A.W., West N.P., Cox A.J. Modulation of allergic inflammation in the nasal mucosa of allergic rhinitis sufferers with topical pharmaceutical agents Front. Pharmacol. 2019; 10: 294. DOI: 10.3389/fphar.2019.00294.

33. Nozad C.H., Michael L.M., Lew D.B. et al. Non-allergic rhinitis: a case report and review. Clin. Mol. Allergy. 2010: 8 (1): 1–9. DOI: 10.1186/1476-7961-8-1.

34. Eifan A.O., Durham S.R. Pathogenesis of rhinitis. Clinical & Experimental Allergy. 2016; 46 (9): 1139–1151. DOI: spiral. imperial.ac.uk:8443/handle/10044/1/37061.

35. Caimmi D., Baiz N., Sanyal S. et al. Discriminating severe seasonal allergic Rhinitis. Results from a large nation-wide database PLoS ONE. 2018; 13 (11): e0207290. DOI: 10.1371/journal.pone.020729.

36. Leung A.K., Hon K.L. Seasonal allergic rhinitis. Recent Pat. Inflamm. Allergy Drug. Discov. 2013; 7 (3): 187–201. DOI: 10.2174/1872213x113079990022.

37. Scadding G.K., Kariyawasam H.H., Scadding G. et al. BSACI guideline for the diagnosis and management of allergic and non-allergic rhinitis (Revised Edition 2017; First edition 2007). Clin. Exp. Allergy. 2017; 47: 856–889. DOI: 10.1111/cea.12953.

38. Galimberti M., Passalacqua G., Incorvaia C. et al. Catching allergy by a simple questionnaire. WAO J. 2015; (8): 1–7. DOI: 10.1186/s40413-015-0067-y.

39. Giavina-Bianchi P. Defining phenotypes in rhinitis: A step toward personalized medicine. J. Allergy Clin. Immunol. 2015; 135: 151–152. DOI: 10.1016/j.jaci.2014.10.029.

40. Papadopoulos N.G., Bernstein J.A., Demoly P. et al. Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report. Allergy. 2015; 70: 474–494. DOI: 10.111/all/12573.

41. De Greve G., Hellings P.W., Fokkens W.J. et al. Endotype-driven treatment in chronic upper airway diseases. Clinical and Тranslational Аllergy. 2017; 7 (22): 1–14. DOI: 10.1186/s13601-017-0157-8.

42. Klimov A.V., Isaev P.Yu., Klimov V.V., Sviridova V.S. Endotypes of allergic rhinitis and asthma accompanying food allergy. Bulletin of Siberian Medicine. 2019; 18 (2): 287–289. DOI: 10.20538/1682-0363-2019-2-287–289.

43. Forester J.P., Calabria C.W. Local production of IgE in the respiratory mucosa and the concept of entopy: Does allergy exist in nonallergic rhinitis? Ann. Allergy Asthma Immunol. 2010; 105 (4): 249–255. DOI: 10.1016/j.anai.2010.02.001.

44. De Mello J.F. Local allergic rhinitis. Braz. J. Otorhinolaryngol .2016; 82 (6): 621–622. DOI: 10.1016/j.bjorl.2016.09.001.

45. Eguiluz-Gracia I., Perez-Sanchez N., Bogas G. et al. How to diagnose and treat local allergic rhinitis: A challenge for clinicians. J. Clin. Med. 2019; 8 (7): 1062– 1074. DOI: 10.3390/jcm8071062.

46. Sennekamp J., Joest I., Filipiak-Pittroff B. et al. Local allergic nasal reactions convert to classic systemic allergic reactions: A long-term follow-up. Int. Arch. Allergy Immunol. 2015; 166: 154–160. DOI: 10.1159/000380852.

47. Krzych-Fałta E., Namysłowski A., Samoliński B. Dilemmas associated with local allergic rhinitis. Adv. Dermatol. Allergol. 2018; 35 (3): 243–245. DOI: 10.5114/ada.2018.76215.

48. Bozek A., Ignasiak B., Kasperska-Zajac A. et al. Local allergic rhinitis in elderly patients. Ann. Allergy Asthma Immunol. 2015; 114 (3): 199–202. DOI: 10.1016/j.anai.2014.12.013.

49. Hellings P.W., Klimek L., Cingi C. et al. Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology. Allergy. 2017; 72: 1657–1665. DOI: 10.1111/all.13200.

50. Rondón C., Campo P., Eguiluz-Gracia I. et al. Local allergic rhinitis is an independent rhinitis phenotype: The results of a 10-year follow-up study. Allergy. 2018; 73 (2): 470–478. DOI: 10.1111/all.13272.

51. Hoyte F.C.L., Nelson H.S. Recent advances in allergic rhinitis. F1000 Research. 2018; 7: 1333. DOI: 10.12688/f1000research.15367.1.

52. Wise S.K., Lin S.Y., Toskala E. et al. International consensus statement on allergy and rhinology: Allergic rhinitis. Int. Forum Allergy Rhinol. 2018; 8 (2): 108–352. DOI: 10.1002/alr.22073.

53. Genuneit J., Seibold A.M., Apfelbacher C.J. et al. Overview of systematic reviews in allergy epidemiology. Allergy. 2017; 72: 849–856. DOI: 10.1111/all.13123.


Для цитирования:


Климов А.В., Kaлюжин О.В., Kлимов В.В., Свиридова В.С. Аллергический ринит и феномен энтопии. Бюллетень сибирской медицины. 2020;19(3):137-143. https://doi.org/10.20538/1682-0363-2020-3-137-143

For citation:


Klimov A.V., Kalyughin O.V., Klimov V.V., Sviridova V.S. Allergic rhinitis and the phenomenon of entopy. Bulletin of Siberian Medicine. 2020;19(3):137-143. https://doi.org/10.20538/1682-0363-2020-3-137-143

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)