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Бюллетень сибирской медицины

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Современные методы радионуклидной диагностики опухолей и неопухолевой патологии головного мозга

https://doi.org/10.20538/1682-0363-2021-4-131-142

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Аннотация

В обзоре обсуждается мировой опыт применения методов ядерной медицины в диагностике опухолей головного мозга и его неопухолевых изменений. Рассматриваются основные группы применяемых сегодня радиофармацевтических препаратов (РФП) для визуализации злокачественных опухолей головного мозга, диагностики когнитивных нарушений и нарушений системы нейротрансмиссии методом однофотонной эмиссионной компьютерной томографии и позитронно-эмиссионной томографии.

В сравнительном аспекте освещаются современные подходы к применению методов радионуклидной диагностики в нейроонкологии и неврологии, отражаются основные тенденции в производстве новых, более специфичных РФП для визуализации опухолей головного мозга различной степени злокачественности и диагностики неопухолевых заболеваний мозга. Обсуждаются преимущества и недостатки применяемых сегодня методик и РФП для визуализации заболеваний центральной нервной системы в зависимости от клинической ситуации и конкретных диагностических задач.

Представлены консолидированные рекомендации ведущих научных школ нейроонкологии по применению методов ядерной медицины у пациентов с опухолями головного мозга на этапах лечения и динамического наблюдения. Рассмотрен опыт отечественных научных школ в разработке РФП для нейроонкологии. Освещены особенности разработки и применения новых РФП у пациентов с опухолями головного мозга и нейродегенеративных заболеваний. Обзор выполнен на анализе литературы, входящей в базы данных Scopus, Web of Science, MedLine, The Cochrane Library, EMBASE, Global Health и РИНЦ. 

Об авторах

Р. В. Зельчан
Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук; Национальный исследовательский Томский политехнический университет (НИ ТПУ)
Россия

канд. мед. наук, ст. науч. сотрудник, отделение радионуклидной диагностики, 634009, г. Томск, пер. Кооперативный, 5;

634050, г. Томск, пр. Ленина, 30



А. А. Медведева
Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук
Россия

канд. мед. наук, ст. науч. сотрудник, отделение радионуклидной диагностики, 

634009, г. Томск, пер. Кооперативный, 5



А. Н. Рыбина
Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук
Россия

канд. мед. наук, врач-рентгенолог, отделение радионуклидной диагностики, 

634009, г. Томск, пер. Кооперативный, 5



О. Д. Брагина
Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук; Национальный исследовательский Томский политехнический университет (НИ ТПУ) 634050, г. Томск, пр. Ленина, 30
Россия

канд. мед. наук, ст. науч. сотрудник, отделение радионуклидной диагностики,

 

634050, г. Томск, пр. Ленина, 30

 



А. И. Рябова
Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук
Россия

канд. мед. наук, науч. сотрудник, отделение опухолей головы и шеи,

634009, г. Томск, пер. Кооперативный, 5



В. И. Чернов
Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук; Национальный исследовательский Томский политехнический университет (НИ ТПУ)
Россия

д-р мед. наук, профессор, зам. директора по научной и инновационной работе, 634009, г. Томск, пер. Кооперативный, 5;

зам. директора по научной и инновационной работе зав. отделением радионуклидной диагностики, 634050, г. Томск, пр. Ленина, 30



Е. Л. Чойнзонов
Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук
Россия

д-р мед. наук, профессор, акад. РАН, директор,

634009, г. Томск, пер. Кооперативный, 5



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Рецензия

Для цитирования:


Зельчан Р.В., Медведева А.А., Рыбина А.Н., Брагина О.Д., Рябова А.И., Чернов В.И., Чойнзонов Е.Л. Современные методы радионуклидной диагностики опухолей и неопухолевой патологии головного мозга. Бюллетень сибирской медицины. 2021;20(4):131-142. https://doi.org/10.20538/1682-0363-2021-4-131-142

For citation:


Zelchan R.V., Medvedeva A.A., Bragina O.D., Ribina A.N., Ryabova A.I., Chernov V.I., Choynzonov E.L. Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain. Bulletin of Siberian Medicine. 2021;20(4):131-142. (In Russ.) https://doi.org/10.20538/1682-0363-2021-4-131-142

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